my response continued:
“cognitive intention - such as top-down attention, or goal-directed imagery - initially stimulates the apical dendritic tufts of pyramidal cells. in the structural hierarchy of the cerebral cortex, these apical tufts terminate in layer 1. . . they function as the primary target for feedback (top-down) signals coming from higher-order cognitive, associative, and motor cortical regions. . . . apical dendritic tufts (top-down): receive feedback representing internal states, including cognitive intentions, behavioral context, predictions, and focused attention. . . . in short, your brain uses the apical dendritic tufts as an entry point for your thoughts, intentions, and focus to actively shape how you perceive and process the physical world. . . . the detector function of cortical pyramidal modules and the integrative properties of apical dendritic tufts are fully compatible, forming a cooperative two-stage computational unit that bridges local processing with global context. . . . pyramidal modules coordinate columns by aligning their superficial tufts within layer 1, allowing synchronous top-down modulatory streams to modulate entire assemblies of vertically stacked cell columns simultaneously.”