One may ask about the inclusion of scientific content in my books and blogs, “So what?” How will a description of the neurophysiological processes of synaptic transmission contribute to understanding the justification and sanctification of repentant individuals by the power of the Holy Spirit? In answer, dualist interactive mechanisms were created by God, and their understanding promises to give clarity to God’s love and grace offered for our redemption at the great cost of his Son, Jesus Christ. It can lead one to accept the reality that the Holy Spirit communicates in our time through the human spirit with the mind and soul of Man through the brain’s synaptic networks.