An understanding of the process of communion between the Holy Spirit and the spirit and soul of Man drawing upon neuroscience will explain the emotional desolation experienced by the God-Man, Jesus Christ, when he was forsaken by the Father while dying on the cross. Jesus recognized that his eternal Father had withdrawn his Spirit from his own human spirit because of the sin burden he carried for all of mankind. The desolation he experienced on the cross in that moment threatens people in our time who disavow the reality of communion between the Holy Spirit and the human spirit and soul and choose to live to Self and its sin nature. It is an eternal outcome. The information shared in Chapter Five of The Boundless Love of God: A Holy Spirit Story, will contribute substance to Christian precepts and can avert such an outcome in the repentant soul of Man.